Knob 1: Turn this to "2" Knob 2: Note that turning this affects Knobs 3&4. Turn this to "7" Knob 3: Turn this to "4" Knob 4: Turn this to "7" Knob 5: Turn this to "1" Knob 2: Turn this one turn to the right, to show "6". This will change dial 3 to "3" and 4 to "8"
Source:
Silent Hill Downpour Safe Puzzle Solution
